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Fatigue can present in many different ways, depending on the individual and the severity of the condition. Some common symptoms of fatigue include:
Fatigue can be caused by a variety of factors, including:
The treatment of fatigue from a functional medicine perspective typically involves a combination of lifestyle changes, dietary modifications, and targeted supplements or medications. Some common treatments for fatigue may include:
Adrenal Fatigue
Adrenal fatigue, known as tired adrenal glands, happens when the adrenal glands cut down hormone production after long-term severe stress or trauma. This mainly affects cortisol and DHEA levels. Initially, the adrenal glands boost cortisol and DHEA production in response to stress. Research shows that prolonged stress leads to a decrease in DHEA. Thus, measuring both cortisol and DHEA is vital to evaluate adrenal function and provide the right support.
DHEA
Low DHEA levels can cause symptoms like fatigue, depression, low libido, and obesity. High levels, on the other hand, might lead to PCOS, acne, and hair loss. People with chronic fatigue syndrome (CFS) commonly have low DHEA levels.
Cortisol
Since cortisol levels fluctuate during the day, it's important to measure them multiple times to get a full picture of adrenal cortisol production. Ideally, cortisol levels should be highest in the morning and decrease as the day progresses. Today, many people show abnormal cortisol patterns, including levels that are too low, high, flat, or even inverted. This test specifically measures bioavailable free cortisol seven times in a single day, as only free cortisol is biologically active.
How Does the Adrenal Test Work?
You receive two saliva test kits to use at home. The cortisol samples are taken seven times in one day, and the DHEA samples twice in the morning. Once you collect the samples, send them to our lab. Your digital test results will be available as soon as our lab finishes analyzing your samples.
GetTested's Vitamin B12 test
GetTested's Vitamin B12 test is designed to accurately trace for B12 in the blood.
Whereas traditional tests measure the total B12 in the body, encompassing both inactive and active forms, GetTested's Vitamin B12 test specifically measures holotranscobalamin, which is the active form of B12. This marker is more sensitive than MMA (methyl malonate), making it a reliable indicator of B12 deficiency.
Measure your B12 levels with our vitamin b12 test kit, delivered to your door and convenient to use at home. If you suspect you may have a Vitamin B12 deficiency, test for B12 now and quickly gain insights into your health.
About Vitamin B12
Vitamin B12, a crucial water-soluble vitamin, plays a vital role in our bodies. Unlike other vitamins, our body cannot produce B12, making dietary intake essential. There are two forms of Vitamin B12: an active form known as Active B12, bound to the protein transcobalamin, and an inactive form. Cells in the body utilise the active form.
One key function of B12 involves DNA production. Without B12, cells cannot divide properly, hindering the replacement of damaged or malfunctioning cells. B12 also contributes to nerve myelination (creating insulating fats around nerves) and breaks down homocysteine, a by-product of protein metabolism.
B12's Unique Absorption Process
Despite being water-soluble, B12 does not dissolve well in water or fat. Its absorption requires a special mechanism involving the intrinsic factor (IF), produced by stomach wall cells. This factor binds to B12, facilitating its transport through the intestinal wall, into the blood, and eventually to the liver. Here, it is stored or distributed throughout the body.
The liver can store B12 for up to 20 years. Unlike other B vitamins, regular B12 intake isn't necessary if liver reserves are sufficient. However, certain groups, including vegans, alcoholics, and individuals who have had bariatric surgery, face a higher risk of B12 deficiency. This risk arises from a potential reduction in intrinsic factor production, crucial for B12 absorption.
Symptoms of a B12 deficiency
A Vitamin B12 deficiency can cause a variety of symptoms that usually develop gradually. If untreated, these conditions can get worse.
Most common symptoms of vitamin B12 include:
Fatigue and weakness
Shortness of breath
Stomach pain
Diarrhoea
Vitamin B12 deficiency can also have an affect on mental well-being and cause:
Headaches,
Feelings of depression
Anxiety
Problems with memory
Symptoms of this deficiency range from mild (like fatigue and weakness) to more severe issues like heart palpitations, aforementioned mental health problems, and neurological symptoms. These symptoms may progress to pernicious anaemia or nerve-related issues like tingling, muscle weakness, and "burning feet syndrome," a result of inadequate myelin formation around nerves.
Vegans and B12 Deficiency
Vitamin B12 naturally occurs in animal-based foods, placing vegans at a heightened risk of deficiency. For vegans, supplementing B12 is vital. The extent of deficiency largely depends on the liver's stored B12 levels at the time of switching to a vegan diet.
About Vitamin D
Vitamin D has many important functions in the body, including supporting the immune system, muscles, and skeletal system. It also plays a role in mental health. Deficiency of Vitamin D can lead to serious conditions, especially if the deficiency persists for a prolonged period. The vitamin helps increase the absorption of calcium, iron, magnesium, phosphate, and zinc in the intestines. There are two main forms of Vitamin D, D3 and D2. Vitamin D3 is naturally produced in the skin when exposed to ultraviolet light, while Vitamin D2 primarily comes from the diet. Almost all cells in the body have receptors for Vitamin D and require sufficient levels to function properly. Vitamin D deficiency can lead to serious health risks such as osteoporosis, osteomalacia, multiple sclerosis, cardiovascular diseases, pregnancy complications, diabetes, depression, stroke, autoimmune diseases, influenza, various forms of cancer, infectious diseases, Alzheimer's, obesity, and more.
During the winter months, especially at northern latitudes, our bodies may have difficulty producing enough Vitamin D due to a lack of sunlight. The risks of Vitamin D deficiency also increase if you have a disease that affects nutrient absorption in the intestines or if you have a limited diet. Vegans and individuals who do not eat fish or enriched foods are at greater risk of Vitamin D deficiency if they do not take supplements.
Symptoms of Vitamin D deficiency
Symptoms of Vitamin D deficiency can be vague and include general fatigue, low mood, weakness, muscle weakness/muscle cramps, digestive problems, and headaches. Prolonged Vitamin D deficiency can lead to serious conditions, particularly affecting the bone tissue of the skeleton, which can result in osteoporosis. Children are particularly sensitive to Vitamin D deficiency as they require adequate levels for proper skeletal development.
Instructions
The kit includes: Test cassette, buffer, lancet, alcohol swab, capillary dropper, leaflet, color card.Preparations: Store the test in the sealed bag at room temperature or in the refrigerator. Do not use after the expiration date.How to take the test: Wash your hands and let the bag reach room temperature. Open the bag and take out the test cassette. Place it on a clean surface. Remove the lancet's cap and use the alcohol swab to clean the fingertip. Pierce the fingertip with the lancet and massage to obtain a blood droplet. Let the blood and capillary dropper come into contact without squeezing. Transfer the blood to the test cassette and add the buffer. Wait for 10 minutes and read the result using the color card. Do not interpret the result immediately or after 20 minutes.
Who is the DNA Fatigue Test Suitable For?
The DNA Fatigue Test is designed for anyone seeking to understand the roots of their fatigue and low energy levels. It's especially valuable for individuals experiencing chronic fatigue, anemia, sleep disturbances, mood swings, and other energy-related issues.
How Does It Work?
Order the Test: Order your GetTested DNA Fatigue Test online and have it delivered to your home.
Collect the Sample: Use the provided test kit to easily collect a saliva sample at home.
Return the Sample: Place the sample in the prepaid return envelope and send it back to the GetTested laboratory.
The Results: Within 6-8 weeks of receiving your sample, we analyze your genes and generate a comprehensive response report.
Test Report and Recommendations
Once your results are ready, you will receive a comprehensive response report from GetTested explaining your genetic insights and what they mean for your health. In addition, the report includes personalized recommendations and strategies to optimize your health based on your genetic results.
About the Sample Material
The DNA and original sample material are destroyed after analysis, and there is no personal connection to the sample except for your unique test ID to which your test results are linked. The information is completely anonymized, and the lab has no knowledge of whom it belongs to. We do not give or sell the results to any third party. You also have the option to remove your test results after receiving them.
About Iron Deficiency and Ferritin
Detect signs of iron deficiency with our high-quality ferritin test. Iron deficiency is common, especially in menstruating women and children, and can have serious health effects. Our test measures the ferritin level (S-Ferritin) in the blood and provides a clear picture of your iron values. If the result is below the threshold of 30 ng/ml, it may indicate potential iron deficiency and could be related to symptoms such as pallor, fatigue, headaches, and shortness of breath during exercise. Sufficient iron stores are crucial for the body to produce enough hemoglobin and red blood cells, which oxygenate your tissues and provide you with energy. Take care of your health and order our ferritin test today to ensure you have a balanced iron level and optimal well-being.
Instructions
Prepare easily for the test by storing it at room temperature or in the refrigerator. Just make sure to use it before the expiration date and keep it in the sealed bag until it's time to use it.
To perform the test, wash your hands thoroughly and let the test cassette reach room temperature. Remove the cap from the lancet and clean the fingertip with the provided alcohol swab. Press the lancet against the finger to obtain a blood sample, and then massage the finger to produce a blood drop.
Use the pipette to collect the blood and place it into the test cassette. Add a drop of buffer solution and wait for the colored lines to appear. After 5 minutes, you can read the result. Remember not to read the result after 10 minutes.

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