Cortisol (total)

Cortisol is the main glucocorticoid hormone produced by the adrenal glands and is often referred to as the “stress hormone.” It plays a crucial role in regulating metabolism, immune response, blood pressure, and the body’s ability to respond to physical and emotional stress. Cortisol follows a daily rhythm, peaking in the early morning to support wakefulness and gradually declining throughout the day. Measuring total cortisol in blood reflects the combined amount of free and protein-bound cortisol, providing insight into adrenal activity and overall hormone balance. Abnormal cortisol levels may be associated with conditions such as adrenal insufficiency, Cushing’s syndrome, chronic stress, or metabolic disorders.

Hormones